The knowledge base does not have a model-specific answer for your exact hard drive, so I can’t confirm compatibility without the drive’s exact model.
What the fragments do say:
- Synology only guarantees full functionality, reliability, and performance for Synology drives listed on the compatibility list. [2], [9]
- For storage systems starting from DSM 7.3 and above, HDDs on the compatibility list and even not listed are supported for new installation and storage pool creation and for migration from existing Synology systems; however, drives on the incompatibility list are not supported. [10]
- For 2.5" SATA SSD, listed and not listed drives are supported for new installation, cache creation, and migration. [10]
- For M.2 NVMe SSD, support is only for migration from existing Synology systems; they are not supported for new installation or storage pool creation. [10]
- Some Synology models have explicit supported drive types in their specifications, for example:
- DS420+: 2.5" SATA SSD, M.2 2280 NVMe SSD [1]
- RS1219+: 3.5" SATA HDD, 2.5" SATA HDD, 2.5" SATA SSD [4]
- RX6022sas: 3.5" Synology SAS HDD or 2.5" Synology SATA SSD [2]
So, in short:
- Yes, non-Synology drives may work, but the knowledge base only guarantees full support for drives on Synology’s compatibility list. [2], [9]
- For exact confirmation, you need to check your drive model against the Synology compatibility list for your NAS. The provided fragments do not include that lookup result.
Sources used: [2], [9], [10], [1], [4]