Side-by-side specifications of the Synology HD6500 and RS6426xs+, from official datasheets. Differences are highlighted.
| HD6500 | RS6426xs+ | |
| CPU | 2× Intel Xeon Silver 4210R, 2.4/3.2 GHz | Intel Xeon D-1739 |
| Cores / threads | 20 cores / 40 threads total | 8 cores / 16 threads |
| RAM (base) | 64 GB DDR4 ECC RDIMM | 16 GB DDR4 ECC RDIMM |
| RAM (max) | 512 GB | 96 GB |
| Drive bays | 60 | 16 |
| Expandable to | 240 (up to 300 total) | 64 |
| M.2 slots | 0 | 0 (via optional adapter card) |
| Network | 2×1GbE + 2×10GbE + 1×out-of-band management | 2 × 10GbE RJ-45 + 1 × out-of-band management LAN |
| 10GbE | yes | yes |
| Max raw capacity | 1 PB single volume / 300 drives | 64 drives |
| Hot-swap | yes | yes |
| Form factor | 4U rackmount | 3U rackmount |
| Released | 2025 | 2026 |
| Power consumption | 1025.2 W / 418 W | 165.45 W / 73.38 W |
| DSM at launch | — | — |
Choose the RS6426xs+ if you want the more balanced 2U chassis with a stronger CPU, more RAM headroom, built-in 10GbE, and M.2 SSD support for cache/volume acceleration. Choose the HD6500 if your priority is raw capacity and expansion: it has far more bays, scales much larger, but is a bigger/more storage-focused system rather than the better all-rounder.