Side-by-side specifications of the Synology RS3621XS+ and RS6426xs+, from official datasheets. Differences are highlighted.
| RS3621XS+ | RS6426xs+ | |
| CPU | Intel Xeon D-1541 | Intel Xeon D-1739 |
| Cores / threads | 8/16 | 8/16 |
| RAM (base) | 8 GB | 16 GB |
| RAM (max) | 64 GB | 96 GB |
| Drive bays | 12 | 16 |
| Expandable to | 36 | 64 |
| M.2 slots | 2 | 2 |
| Network | 4x 1GbE/10GbE RJ-45 | 2x 10GbE RJ-45 |
| 10GbE | yes | yes |
| Max raw capacity | 1 PB | 1 PB |
| Hot-swap | yes | yes |
| Form factor | 2U | 3U rack |
| Released | 2025 | 2026 |