Especificaciones de los Synology RS2418+ y RS2421+ en paralelo, de las fichas técnicas oficiales. Las diferencias están resaltadas.
| RS2418+ | RS2421+ | |
| CPU | Intel Atom C3538 | AMD Ryzen V1500B |
| Núcleos / hilos | 4 cores / 4 threads | 4 cores / 8 threads |
| RAM (base) | 4 GB DDR4 non-ECC UDIMM | 4 GB DDR4 ECC UDIMM |
| RAM (máx.) | 64 GB | 32 GB |
| Bahías | 12 | 12 |
| Ampliable a | 12 (up to 24 total with RX1217/RX1217RP) | 24 total with 1 RX1217/RX1217RP |
| Ranuras M.2 | 0; optional M.2 SATA adapter card | 0 internal; via PCIe adapter |
| Red | 4 x 1GbE RJ-45 | 4 x 1GbE RJ-45 |
| 10GbE | optional | optional |
| Capacidad bruta máx. | 144 TB internal; 288 TB with 1 expansion unit | 108 TB single volume; 24 bays with expansion |
| Intercambio en caliente | yes | yes |
| Formato | 2U rackmount | Rackmount 2U |
| Lanzamiento | 2018 | 2021 |
| Consumo | 109 W / 52.4 W | — |
| DSM de lanzamiento | 6.2 | — |