Side-by-side specifications of the Synology RS1221RP+ and RS1626xs+, from official datasheets. Differences are highlighted.
| RS1221RP+ | RS1626xs+ | |
| CPU | AMD Ryzen V1500B | Intel Xeon D-1726 |
| Cores / threads | 4 cores / 8 threads | 6 cores / 12 threads |
| RAM (base) | 4 GB DDR4 ECC SODIMM | 16 GB DDR4 ECC RDIMM |
| RAM (max) | 32 GB | 64 GB |
| Drive bays | 8 | 4 |
| Expandable to | 12 with RX418 | 16 total with RX1225RP |
| M.2 slots | 0; optional adapter card | 2 NVMe |
| Network | 4× 1GbE RJ-45 | 2 x 10GbE RJ-45; 1 x out-of-band management LAN |
| 10GbE | optional | yes |
| Max raw capacity | 108 TB single volume | Unknown |
| Hot-swap | yes | yes |
| Form factor | 2U rackmount | 1U rackmount |
| Released | 2020 | 2026 |
| Power consumption | 61.94 W / 29.98 W | 97.59 W / 56.19 W |
| DSM at launch | — | — |