Side-by-side specifications of the Synology RS1221+ and RS816, from official datasheets. Differences are highlighted.
| RS1221+ | RS816 | |
| CPU | AMD Ryzen V1500B | Marvell ARMADA 385 88F6820 1.8GHz |
| Cores / threads | 4 cores / 8 threads | 2 cores / 2 threads |
| RAM (base) | 4 GB DDR4 ECC SODIMM | 1 GB DDR3 |
| RAM (max) | 32 GB | 1 GB |
| Drive bays | 8 | 4 |
| Expandable to | 12 total with RX418 | 0 |
| M.2 slots | 0 built-in; optional adapter card | 0 |
| Network | 4 × 1GbE RJ-45 | 2x Gigabit Ethernet |
| 10GbE | optional | no |
| Max raw capacity | 108 TB single volume | 56 TB |
| Hot-swap | yes | yes |
| Form factor | 2U rackmount | 1U rackmount |
| Released | 2021 | 2016 |
| Power consumption | 49.89 W / 22.64 W | — |
| DSM at launch | — | — |