Especificaciones de los Synology HD6500 y RS3621xs+ en paralelo, de las fichas técnicas oficiales. Las diferencias están resaltadas.
| HD6500 | RS3621xs+ | |
| CPU | 2× Intel Xeon Silver 4210R, 2.4/3.2 GHz | Intel Xeon D-1541 |
| Núcleos / hilos | 20 cores / 40 threads total | 8 cores / 16 threads |
| RAM (base) | 64 GB DDR4 ECC RDIMM | 8 GB DDR4 ECC UDIMM |
| RAM (máx.) | 512 GB | 64 GB |
| Bahías | 60 | 12 |
| Ampliable a | 240 (up to 300 total) | 36 |
| Ranuras M.2 | 0 | 0 (via PCIe adapter cards) |
| Red | 2×1GbE + 2×10GbE + 1×out-of-band management | 4×1GbE RJ-45, 2×10GbE RJ-45 |
| 10GbE | yes | yes |
| Capacidad bruta máx. | 1 PB single volume / 300 drives | 1 PB single volume |
| Intercambio en caliente | yes | yes |
| Formato | 4U rackmount | 2U rackmount |
| Lanzamiento | 2025 | 2021 |
| Consumo | 1025.2 W / 418 W | — |
| DSM de lanzamiento | — | — |