Side-by-side specifications of the Synology DS1621+ and DS1817, from official datasheets. Differences are highlighted.
| DS1621+ | DS1817 | |
| CPU | AMD Ryzen V1500B, 2.2 GHz | Intel Atom C2538 1.7 GHz |
| Cores / threads | 4 cores / 8 threads | quad-core/4 threads |
| RAM (base) | 4 GB DDR4 ECC SODIMM | 4 GB |
| RAM (max) | 32 GB (16 GB x 2) | 8 GB |
| Drive bays | 6 | 8 |
| Expandable to | 16 total with 2 DX517 units | 10 |
| M.2 slots | 2 x M.2 2280 NVMe | 0 |
| Network | 4 x 1GbE RJ-45 | 2 x 1GbE RJ-45, 2 x 10GBASE-T RJ-45 |
| 10GbE | optional | yes |
| Max raw capacity | 256 TB raw with 2 DX517 units | 180 TB |
| Hot-swap | yes | yes |
| Form factor | desktop | desktop |
| Released | 2020 | 2017 |
| Power consumption | 51.22 W / 25.27 W | — |
| DSM at launch | — | — |