Side-by-side specifications of the Synology DS1522+ and DS1621xs+, from official datasheets. Differences are highlighted.
| DS1522+ | DS1621xs+ | |
| CPU | AMD Ryzen R1600 2.6 GHz, up to 3.1 GHz | Intel Xeon D-1527 2.2/2.7 GHz |
| Cores / threads | 2 cores / 4 threads | 4 cores / 8 threads |
| RAM (base) | 8 GB DDR4 ECC SODIMM | 8 GB DDR4 ECC SODIMM |
| RAM (max) | 32 GB | 32 GB |
| Drive bays | 5 | 6 |
| Expandable to | 10 | 16 total with 2× DX517 |
| M.2 slots | 2 M.2 2280 NVMe | 2× M.2 2280 NVMe |
| Network | 4 x 1GbE RJ-45 | 2× 1GbE RJ-45, 1× 10GbE RJ-45 |
| 10GbE | optional | yes |
| Max raw capacity | 15 drives | 96 TB internal; 256 TB with 2× DX517 |
| Hot-swap | yes | yes |
| Form factor | Desktop | Tower |
| Released | 2021 | 2020 |
| Power consumption | 52.06 W / 16.71 W | — |
| DSM at launch | — | — |